ALEXEY S. KUZNETSOV Assistant Professor Department of Mathematical Sciences • Indiana University & Purdue University Indianapolis 402 N. Blackford St. • Indianapolis, IN 46204, USA •• (317) 278-7460
| EDUCATION: | Nizhny Novgorod State University, Nizhny Novgorod, Russia |
| 6/96 – 7/99 |
PhD equivalent in Physics and Mathematics
• Dissertation Title: Dynamics in ensembles of bistable elements with nonlinear couplings (suppression of oscillations, cluster formation, synchronization). |
| 6/94 – 5/96 |
M.S. in Physics with Honors
• Studied Dynamical Systems, Differential Equations, Bifurcation Theory. |
| 6/90 – 5/94 |
B.S. in Physics • Learned Theory of Oscillations and Waves, Active Media, Solitons. |
| EXPERIENCE: |
|
| 18/05-present |
Assistant professor, Department of Mathematical Sciences, IUPUI
• Mathematical modeling in neuroscience and molecular biology. |
| 1/02 – 7/05 |
Postdoctoral Research Associate, Center for BioDynamics and Mathematics Department, Boston University, Boston, MA, USA
• Modeled and analyzed dynamics in a population of cells encapsulating genetic oscillatory networks (joint with Biomedical Engineering Dept., BU) • Investigated firing patterns of the dopaminergic neuron (joint with Biology Department, UTSA) • Learned theoretical cell biology, genetics and neuroscience • Observed and analyzed experiments |
| 7/01 – 11/01 |
Visiting Scientist, Physics Department, University of Potsdam; Potsdam, Germany
• Studied intermittent formation of synchronous clusters based on a stable heteroclinic cycle |
| 8/99 – 03/03 |
Research Associate, Division of Nonlinear Dynamics, Institute of Applied Physics, Russian Academy of Sciences (IAP RAS), Nizhny Novgorod, Russia
• Modeled locomotor-like movements of human evoked by muscle vibration • Studied influence of connectivity in a network of active elements on its dynamics |
| 11/98 – 07/99 |
Junior Research Associate, IAP RAS, Prof. Vladimir D. Shalfeev
• Investigated suppression of oscillations and cluster formation in a network of globally coupled active bistable elements |
| 11/95 – 10/98 |
Research Assistant, IAP RAS, Prof. Vladimir D. Shalfeev
• Studied formation and recovery of clusters in a network with chaotic, asynchronous behavior |
| Teaching | |
| 2005-present |
Assistant professor, IUPUI
Courses: Calculus for Technology I and II; Calculus for Life Sciences I; Qualitative Theory of Differential Equations • Lecturing and giving exams |
| 2003,04 |
Lecturer, Boston University
Courses: Calculus I (Fall 2003), Linear Algebra (Fall 2004) • Lecturing, leading discussion sections, giving exams, and grading |
| 1996-98 |
Teaching Assistant, Nizhny Novgorod State University
Courses: Classical Mechanics (Fall 1996,97,98) • Leading discussion sections and helping prepare exams |
| RECENT PRESENTATIONS: | |
| 11/2007 | • Society for Neuroscience (SFN) Annual Meeting 2007, San Diego, CA; • Bursting and Pacemaking in a Coupled Oscillator Model of the Dopamine Neuron,poster. |
| 7/2007 | • Computational Neuroscience (CNS) Annual Meeting 2007, Toronto, Canada; • Realistic Synaptic Inputs Applied to Coupled Oscillator Model of the Dopaminergic Neuron,poster. |
| 4/2007 | • MBI, OSU, Columbus, OH; • What drives midbrain dopaminergic neurons to oscillate at high frequencies? seminar. |
| 10/2006 | • SFN 2006, Atlanta, GA; • High-frequency firing in midbrain dopaminergic neurons is activated by dendritic NMDA, but not AMPA receptor: a modeling study,poster. |
| 7/2006 | • CNS 2006, Edinburgh, UK; • A mechanism for NMDA-activated high-frequency firing in midbrain dopaminergic neurons, presentation. |
| 11/2004 | • MBI, OSU, Columbus, OH; • Modeling of high-frequency transient in dopamine neuron: dynamical mechanisms and role of dendritic geometry, seminar. |
| 10/2004 | • SFN 2004, San Diego, CA; • Modeling of transient firing of nigral dopamine neuron in vivo and in slices, poster. |
| 7/2004 | • CNS 2004, Baltimore, MD; Workshop on Theoretical Approaches to Basal Ganglia Function. • Modeling of transient firing of the mesencephalic dopamine neuron in vivo and in slices, presentationon. |
| 7/2004 |
• SIAM Conference on the Life Sciences, Portland, OR; Minisymposium on Canards in the Life Sciences II: Neuronal Patterns and Dynamics. • High-frequency Transient Dynamics for a Coupled Oscillators Model of a Dopamine Neuron, invited presentation.
|
| SELECTED PUBLICATIONS: | • A. Kuznetsov, L. Rubchinsky, N. Kopell, C. Wilson, Models of Midbrain Dopaminergic Neurons. Scholarpedia, pp.23551, 2007. |
| • L.Rubchinsky A. Kuznetsov, V. Wheelock, K. Sigvardt, Tremor. Scholarpedia, pp. 22658, 2007. | |
| • A. Kuznetsov, N.Kopell, C. Wilson, Transient High-Frequency Firing in a Coupled-Oscillator Model of the Mesencephalic Dopaminergic Neuron J.Neurophysiology 95(2) pp. 932-947, 2006. | |
| • A. Kuznetsov, G.L. Forty, V.D. Shalfeev, Analysis of Pattern Formation in a Chain of Coupled Bistable Elements. Int. J. Bifurcation and Chaos 16(3): 741-747, 2006. | |
| • A.S. Kuznetsov, V.D. Shalfeev, L.S. Tsimring, Regularization of Dynamics in an Ensemble of Nondiffusively Coupled Chaotic Elements PRE 72, p. 046209, 2005. | |
| • A. Kuznetsov, M. Kaern, N. Kopell, Synchrony in a Population of Hysteresis-based Genetic Oscillators SIAM J. Applied Math., 65(2) pp. 392-425, 2004. | |
| • A.S. Kuznetsov, J. Kurths, 2002, Stable Heteroclinic Cycles for ensembles of chaotic oscillators PRE 66 p. 026201. |
| GRANTS: | |
| 2008-2009 | IUPUI International Development Fund; Dynamical modeling of oscillatory regulatory networks |
| 2007-2008 | Indiana University RSFG; Activity of Basal Ganglia Networks in Parkinson's disease: laying the foundation for adaptive brain stimulation |
| 7-10/2001 | Fellowship for Visiting Scientist, German Academic Exchange Service (DAAD) |
| 2001 | Personal Grant for Young Scientist, Russian Foundation for Fundamental Research |