ALEXEY   S.  KUZNETSOV
Assistant Professor

Department of Mathematical Sciences  •   Indiana University & Purdue University Indianapolis
402 N. Blackford St. •  Indianapolis, IN 46204, USA  •    •  (317) 278-7460
EDUCATION: Nizhny Novgorod State University, Nizhny Novgorod, Russia
6/96 – 7/99 PhD equivalent in Physics and Mathematics
Dissertation Title: Dynamics in ensembles of bistable elements with nonlinear couplings (suppression of oscillations, cluster formation, synchronization).
6/94 – 5/96 M.S. in Physics with Honors
Studied Dynamical Systems, Differential Equations, Bifurcation Theory.
6/90 – 5/94 B.S. in Physics
Learned Theory of Oscillations and Waves, Active Media, Solitons.

EXPERIENCE: Research
18/05-present Assistant professor, Department of Mathematical Sciences, IUPUI
Mathematical modeling in neuroscience and molecular biology.
1/02 – 7/05 Postdoctoral Research Associate, Center for BioDynamics and Mathematics Department, Boston University, Boston, MA, USA
Modeled and analyzed dynamics in a population of cells encapsulating genetic oscillatory networks (joint with Biomedical Engineering Dept., BU)
Investigated firing patterns of the dopaminergic neuron (joint with Biology Department, UTSA)
Learned theoretical cell biology, genetics and neuroscience
Observed and analyzed experiments
7/01 – 11/01 Visiting Scientist, Physics Department, University of Potsdam; Potsdam, Germany
Studied intermittent formation of synchronous clusters based on a stable heteroclinic cycle
8/99 – 03/03 Research Associate, Division of Nonlinear Dynamics, Institute of Applied Physics, Russian Academy of Sciences (IAP RAS), Nizhny Novgorod, Russia
Modeled locomotor-like movements of human evoked by muscle vibration
Studied influence of connectivity in a network of active elements on its dynamics
11/98 – 07/99 Junior Research Associate, IAP RAS, Prof. Vladimir D. Shalfeev
Investigated suppression of oscillations and cluster formation in a network of globally coupled active bistable elements
11/95 – 10/98 Research Assistant, IAP RAS, Prof. Vladimir D. Shalfeev
Studied formation and recovery of clusters in a network with chaotic, asynchronous behavior
Teaching
2005-present Assistant professor, IUPUI
Courses: Calculus for Technology I and II; Calculus for Life Sciences I; Qualitative Theory of Differential Equations
Lecturing and giving exams
2003,04 Lecturer, Boston University
Courses: Calculus I (Fall 2003), Linear Algebra (Fall 2004)
Lecturing, leading discussion sections, giving exams, and grading
1996-98 Teaching Assistant, Nizhny Novgorod State University
Courses: Classical Mechanics (Fall 1996,97,98)
Leading discussion sections and helping prepare exams

RECENT PRESENTATIONS:
11/2007 Society for Neuroscience (SFN) Annual Meeting 2007, San Diego, CA; • Bursting and Pacemaking in a Coupled Oscillator Model of the Dopamine Neuron,poster.
7/2007 Computational Neuroscience (CNS) Annual Meeting 2007, Toronto, Canada; • Realistic Synaptic Inputs Applied to Coupled Oscillator Model of the Dopaminergic Neuron,poster.
4/2007 MBI, OSU, Columbus, OH; • What drives midbrain dopaminergic neurons to oscillate at high frequencies? seminar.
10/2006 SFN 2006, Atlanta, GA; • High-frequency firing in midbrain dopaminergic neurons is activated by dendritic NMDA, but not AMPA receptor: a modeling study,poster.
7/2006 CNS 2006, Edinburgh, UK; • A mechanism for NMDA-activated high-frequency firing in midbrain dopaminergic neurons, presentation.
11/2004 MBI, OSU, Columbus, OH; • Modeling of high-frequency transient in dopamine neuron: dynamical mechanisms and role of dendritic geometry, seminar.
10/2004 SFN 2004, San Diego, CA; • Modeling of transient firing of nigral dopamine neuron in vivo and in slices, poster.
7/2004 CNS 2004, Baltimore, MD; Workshop on Theoretical Approaches to Basal Ganglia Function. • Modeling of transient firing of the mesencephalic dopamine neuron in vivo and in slices, presentationon.
7/2004 SIAM Conference on the Life Sciences, Portland, OR; Minisymposium on Canards in the Life Sciences II: Neuronal Patterns and Dynamics. • High-frequency Transient Dynamics for a Coupled Oscillators Model of a Dopamine Neuron, invited presentation. Minisymposium on Switches and Oscillators in Genetic Circuits. • Robust Synchronization and Symmetry Breaking in an Oscillatory Gene Network, invited presentation.

SELECTED PUBLICATIONS: A. Kuznetsov, L. Rubchinsky, N. Kopell, C. Wilson, Models of Midbrain Dopaminergic Neurons. Scholarpedia, pp.23551, 2007.
L.Rubchinsky A. Kuznetsov, V. Wheelock, K. Sigvardt, Tremor. Scholarpedia, pp. 22658, 2007.
A. Kuznetsov, N.Kopell, C. Wilson, Transient High-Frequency Firing in a Coupled-Oscillator Model of the Mesencephalic Dopaminergic Neuron J.Neurophysiology 95(2) pp. 932-947, 2006.
A. Kuznetsov, G.L. Forty, V.D. Shalfeev, Analysis of Pattern Formation in a Chain of Coupled Bistable Elements. Int. J. Bifurcation and Chaos 16(3): 741-747, 2006.
A.S. Kuznetsov, V.D. Shalfeev, L.S. Tsimring, Regularization of Dynamics in an Ensemble of Nondiffusively Coupled Chaotic Elements PRE 72, p. 046209, 2005.
A. Kuznetsov, M. Kaern, N. Kopell, Synchrony in a Population of Hysteresis-based Genetic Oscillators SIAM J. Applied Math., 65(2) pp. 392-425, 2004.
A.S. Kuznetsov, J. Kurths, 2002, Stable Heteroclinic Cycles for ensembles of chaotic oscillators PRE 66 p. 026201.

GRANTS:
2008-2009 IUPUI International Development Fund; Dynamical modeling of oscillatory regulatory networks
2007-2008 Indiana University RSFG; Activity of Basal Ganglia Networks in Parkinson's disease: laying the foundation for adaptive brain stimulation
7-10/2001 Fellowship for Visiting Scientist, German Academic Exchange Service (DAAD)
2001 Personal Grant for Young Scientist, Russian Foundation for Fundamental Research